Structural and functional characterization of human apolipoprotein E 72-166 peptides in both aqueous and lipid environments
Abstract Backgrounds There are three apolipoprotein E (apoE) isoforms involved in human lipid homeostasis.In the present study, truncated apoE2-, apoE3- and apoE4-(72-166) peptides that are tailored to lack domain interactions are expressed SCISSORS and elucidated the structural and functional consequences.Methods & Results Circular dichroism analy